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CI74

Recombinant Human 6-phosphogluconate dehydrogenase, decarboxylating/PGD

10ug

560

504

现货

国产

CI74

Recombinant Human 6-phosphogluconate dehydrogenase, decarboxylating/PGD

50ug

2120

1908

现货

国产

CI74

Recombinant Human 6-phosphogluconate dehydrogenase, decarboxylating/PGD

500ug

12320

11088

现货

国产

CI74

Recombinant Human 6-phosphogluconate dehydrogenase, decarboxylating/PGD

1mg

17600

15840

现货

国产

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  • Catalog# CI74
    Source Human cells
    Description Recombinant Human PGD is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Ala483) of Human PGD fused with a polyhistidine tag at the C-terminus.
    Names 6-phosphogluconate dehydrogenase, decarboxylating,PGD,PGDH
    Accession # P52209
    Formulation Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKL KKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSG GEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDM QLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQ KGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRK ALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLL LDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTY ELLAKPGQFIHTNWTGHGGTVSSSSYNAVDHHHHHH
    Background 6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein, and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH. Mutations within the gene coding this enzyme result in 6-phosphogluconate dehydrogenase deficiency, an autosomal hereditary disease effecting the red blood cells.