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CI89
Recombinant Human Adiponectin/Acrp30/ADIPOQ
10ug
760
684
现货
国产
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CI89
Recombinant Human Adiponectin/Acrp30/ADIPOQ
50ug
2000
1800
现货
国产
-
CI89
Recombinant Human Adiponectin/Acrp30/ADIPOQ
500ug
12320
11088
现货
国产
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CI89
Recombinant Human Adiponectin/Acrp30/ADIPOQ
1mg
17600
15840
现货
国产
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Catalog# CI89 Source E. coli Description Recombinant Mouse Acrp30 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu17-Asn247) of Mouse Acrp30 fused with a polyhistidine tag at the C-terminus. Names Adiponectin, 30 kDa Adipocyte Complement-Related Protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and Collagen Domain-Containing Protein, Adipose Most Abundant Gene Transcript 1 Protein, apM-1, Gelatin-Binding Protein, ADIPOQ Accession # Q60994 Formulation Supplied as a 0.2 μM filtered solution of 20mM PB,150mM NaCl,pH7.4 Shipping The product is shipped at ambient temperature. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence EDDVTTTEELAPALVPPPKGTCAGWMAGIPGHPGHNGTPGRDGRDGTPGEKGEKGDAGLLGPKGE TGDVGMTGAEGPRGFPGTPGRKGEPGEAAYVYRSAFSVGLETRVTVPNVPIRFTKIFYNQQNHYD GSTGKFYCNIPGLYYFSYHITVYMKDVKVSLFKKDKAVLFTYDQYQEKNVDQASGSVLLHLEVGD QVWLQVYGDGDHNGLYADNVNDSTFTGFLLYHDTNHHHHHHBackground Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.