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CJ06

Recombinant Human CD112/nectin2/Pvrl2/Pvr/Mph/Pvs

10ug

760

684

现货

国产

CJ06

Recombinant Human CD112/nectin2/Pvrl2/Pvr/Mph/Pvs

50ug

2280

2052

现货

国产

CJ06

Recombinant Human CD112/nectin2/Pvrl2/Pvr/Mph/Pvs

500ug

12320

11088

现货

国产

CJ06

Recombinant Human CD112/nectin2/Pvrl2/Pvr/Mph/Pvs

1mg

17600

15840

现货

国产

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  • Catalog# CJ06
    Source Human cells
    Description Recombinant mouse CD112/nectin2 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln32-Gly351) of mouse CD112/nectin2 fused with a polyhistidine tag at the C-terminus.
    Names CD112/nectin2 /Herpes virus entry mediator B/Herpesvirus entry mediator B/HveB/Murine herpes virus entry protein B/mHveB/Poliovirus receptor homolog/Poliovirus receptor-related protein 2/Pvrl2/Pvr/Mph/Pvs
    Accession # P32507
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 3X PBS.
    Please aliquot the reconstituted solution
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 5 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    QDVRVRVLPEVRGRLGGTVELPCHLLPPTTERVSQVTWQRLDGTVVAAFHPSFGVDFPNSQFSKD RLSFVRARPETNADLRDATLAFRGLRVEDEGNYTCEFATFPNGTRRGVTWLRVIAQPENHAEAQE VTIGPQSVAVARCVSTGGRPPARITWISSLGGEAKDTQEPGIQAGTVTIISRYSLVPVGRADGVK VTCRVEHESFEEPILLPVTLSVRYPPEVSISGYDDNWYLGRSEAILTCDVRSNPEPTDYDWSTTS GVFPASAVAQGSQLLVHSVDRMVNTTFICTATNAVGTGRAEQVILVRESPSTAGAGATGGVDHHH HHH*
    Background Nectin-2( CD112) is a member of the nectin family, which contains two Ig-like C2-type domains and one Ig-like V-type domain in the extracellular region. Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Nectin2 is widely expressed in human tissues including brain, spinal cord, spleen, kidney, heart and liver. It can form trans-heterodimers with PVRL3/nectin-3 and interacts with CD226. Mutations of alleles of the murine CD112 gene can result in conditions such as morphologically aberrant spermatozoa. It may function in allergic reactions, and accordingly may used as a novel target for anti-allergic therapy.