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CH44
Recombinant Human Complement component C8 gamma chain/C8G
10ug
1200
1080
现货
国产
-
CH44
Recombinant Human Complement component C8 gamma chain/C8G
50ug
3520
3168
现货
国产
-
CH44
Recombinant Human Complement component C8 gamma chain/C8G
500ug
12320
11088
现货
国产
-
CH44
Recombinant Human Complement component C8 gamma chain/C8G
1mg
17600
15840
现货
国产
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Catalog# CH44 Source E.coli Description Recombinant Human C8G is produced with our E. coli expression system. The target protein is expressed with sequence (Gln21-Arg202) of Human C8G fused with a polyhistidine tag at the N-terminus. Names Complement component C8 gamma chain,C8G Accession # P07360 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0. Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMQKPQRPRRPASPISTIQPKANFDAQQFAGTWLLVAVGSACRFLQ EQGHRAEATTLHVAPQGTAMAVSTFRKLDGICWQVRQLYGDTGVLGRFLLQARGARGAVNVVVAE TDYQSFAVLYLERAGQLSVKLYARSLPVSDSVLSGFEQRVQEAHLTEDQIFYFPKYGFCEAADQF HVLDEVRR*Background Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.