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CH51

Recombinant Human Ferritin heavy chain/FTH1

10ug

400

360

现货

国产

CH51

Recombinant Human Ferritin heavy chain/FTH1

50ug

1120

1008

现货

国产

CH51

Recombinant Human Ferritin heavy chain/FTH1

500ug

6720

6048

现货

国产

CH51

Recombinant Human Ferritin heavy chain/FTH1

1mg

9600

8640

现货

国产

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  • Catalog# CH51
    Source E.coli
    Description Recombinant Human FTH1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser183) of Human FTH1 fused with a polyhistidine tag at the N-terminus.
    Names Ferritin heavy chain,FTH1,FTH,FTHL6,Ferritin H subunit,Cell proliferation-inducing gene 15 protein
    Accession # P02794
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRD DVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKN VNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHT LGDSDNES*
    Background Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and release in different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost all living organisms can produce this protein, including algae, bacteria, higher plants, and animals.