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CH77
Recombinant Human Glia maturation factor beta/GMFB
10ug
560
504
现货
国产
-
CH77
Recombinant Human Glia maturation factor beta/GMFB
50ug
2120
1908
现货
国产
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CH77
Recombinant Human Glia maturation factor beta/GMFB
500ug
12320
11088
现货
国产
-
CH77
Recombinant Human Glia maturation factor beta/GMFB
1mg
17600
15840
现货
国产
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Catalog# CH77 Source E.coli Description Recombinant Human Glia maturation factor beta is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-His142) of Human GMFB fused with a 6His tag at the C-terminus. Names Glia maturation factor beta，GMF-beta, GMFB Accession # P60983 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris,200mMNaCl,pH8.0 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MSESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEGISPDELKDELPERQ PRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLT EEWLREKLGFFHLEHHHHHH*Background Glia maturation factor beta (GMFB) contains a ADF-H domain，which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.