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CH75

Recombinant Human Heat shock protein beta-8/HSPB8

10ug

1200

1080

现货

国产

CH75

Recombinant Human Heat shock protein beta-8/HSPB8

50ug

3520

3168

现货

国产

CH75

Recombinant Human Heat shock protein beta-8/HSPB8

500ug

12320

11088

现货

国产

CH75

Recombinant Human Heat shock protein beta-8/HSPB8

1mg

17600

15840

现货

国产

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  • Catalog# CH75
    Source E.coli
    Description Recombinant Human HSPB8 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Thr196) of Human HSPB8 fused with a polyhistidine tag at the C-terminus.
    Names Heat shock protein beta-8,HspB8,Alpha-crystallin C chain,E2-induced gene 1 protein,Protein kinase H11,Small stress protein-like protein HSP22,HSPB8,CRYAC,E2IG1,HSP22
    Accession # Q9UJY1
    Formulation Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAWPGTLR SGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQ EGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELPQDSQEVTC TLEHHHHHH
    Background Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.