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CH67
Recombinant Human HMGB1/High mobility group protein B1
10ug
1200
1080
现货
国产
-
CH67
Recombinant Human HMGB1/High mobility group protein B1
50ug
3520
3168
现货
国产
-
CH67
Recombinant Human HMGB1/High mobility group protein B1
500ug
12320
11088
现货
国产
-
CH67
Recombinant Human HMGB1/High mobility group protein B1
1mg
17600
15840
现货
国产
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Catalog# CH67 Source E.coli Description Recombinant Human High mobility group protein B1 is produced with our E. coli expression system. The target protein is expressed with sequence (Pro92-Val176) of Human HMGB1 fused with a MART tag at the N-terminus. Names High Mobility Group Protein B1, High Mobility Group Protein 1, HMG-1, HMGB1, HMG1 Accession # P09429 Formulation Lyophilized from a 0.2 μm filtered solution of 50mM HEPES,500mM NaCl,0.6mM DTT,pH 7.9 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MARIDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKL KEKYEKDIAAYRAKGKPDAAKKGVVBackground High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.