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CH84
Recombinant Human Pro-neuregulin-1/NRG1?beta 1
10ug
1400
1260
现货
国产
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CH84
Recombinant Human Pro-neuregulin-1/NRG1?beta 1
50ug
3600
3240
现货
国产
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CH84
Recombinant Human Pro-neuregulin-1/NRG1?beta 1
500ug
12320
11088
现货
国产
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CH84
Recombinant Human Pro-neuregulin-1/NRG1?beta 1
1mg
17600
15840
现货
国产
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Catalog# CH84 Source E.coli Description Recombinant Human Pro-neuregulin-1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Lys246) of Human NRG1. Names Pro-neuregulin-1,Neuregulin-1 beta 1,NRG1-beta 1,HRG1-beta 1 ECD,EGF,NRG1, GGF, HGL, HRGA, NDF, SMDF, Accession # Q02297-6 Formulation Lyophilized from a 0.2 μm filtered solution of 4mM HCl Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPQLKEMKSQ ESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEY MCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTG TSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEA EELYQKBackground neuregulin-1 (heregulin-1，NRG1) is a member of neuregulin family, which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. NRG1 isoforms can be classified into type I, type II and type III isoforms. NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.