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CI92
Recombinant Human Sedoheptulokinase/SHPK/CARKL
10ug
936
842.4
现货
国产
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CI92
Recombinant Human Sedoheptulokinase/SHPK/CARKL
50ug
3520
3168
现货
国产
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CI92
Recombinant Human Sedoheptulokinase/SHPK/CARKL
500ug
12320
11088
现货
国产
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CI92
Recombinant Human Sedoheptulokinase/SHPK/CARKL
1mg
17600
15840
现货
国产
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Catalog# CI92 Source Human cells Description Recombinant Human SHPK is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Ser478) of Human SHPK fused with a polyhistidine tag at the C-terminus. Names Sedoheptulokinase,SHK,Carbohydrate kinase-like protein,SHPK,CARKL Accession # Q9UHJ6 Formulation Supplied as a 0.2 μM filtered solution of 20mM PB,150mM NaCl,pH7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MAARPITLGIDLGTTSVKAALLRAAPDDPSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRI LQALHECLAALPRPQLRSVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDG RCSSEFLASLPQPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAAGTIHDYVVAMLCGLPRPLMS DQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRTSHMWFEIPKGTQVGVALGDL QASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDPTAPVAYFPYFNRTYLGVAASLNGGN VLATFVHMLVQWMADLGLEVEESTVYSRMIQAAVQQRDTHLTITPTVLGERHLPDQLASVTRISS SDLSLGHVTRALCRGIVQNLHSMLPIQQLQEWGVERVMGSGSALSRNDVLKQEVQRAFPLPMSFG QDVDAAVGAALVMLRRHLNQKESVDHHHHHHBackground Sedoheptulokinase (SHPK) belongs to the FGGY kinase family, and is mainly located in cytoplasm. SHPK is strongly expressed in liver, kidney and pancreas. It is expressed at lower levels in placenta and heart, and very weakly expressed in lung and brain. SHPK catalyzes the chemical reaction: ATP + sedoheptulose = ADP + sedoheptulose 7-phosphatecan, It can transform sedoheptulose to sedoheptulose 7-phosphate in the condition of ATP, and acts as a modulator of macrophage activation through control of glucose metabolism. In addition, It also can be down-regulated by LPS.