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CJ01
Recombinant Human SERPINB1/Serpin B1/ELANH2/MNEI/PI2
10ug
936
842.4
现货
国产
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CJ01
Recombinant Human SERPINB1/Serpin B1/ELANH2/MNEI/PI2
50ug
3520
3168
现货
国产
-
CJ01
Recombinant Human SERPINB1/Serpin B1/ELANH2/MNEI/PI2
500ug
12320
11088
现货
国产
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CJ01
Recombinant Human SERPINB1/Serpin B1/ELANH2/MNEI/PI2
1mg
17600
15840
现货
国产
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Catalog# CJ01 Source E. coli Description Recombinant Human SERPINB1/Leukocyte elastase inhibitor/LEI is produced with our Mammalian expression system. The target protein is expressed with sequence (Met1-Pro379) of Human Serpin B1 fused with a 6His tag at the C-terminus. Names SERPINB1/Leukocyte elastase inhibitor/LEI/Monocyte/neutrophil elastase inhibitor/EI/M/NEI/Peptidase inhibitor 2/PI-2/Serpin B1/ELANH2/MNEI/PI2 Accession # P30740 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 2X PBS.
Please aliquot the reconstituted solution䠀ŒѦStorage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 4 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVEE VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARK TINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTV KMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTK PENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVE VNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSPVDHHHHHHBackground SERPINB1 is a member of the serpin family and Ov-serpin subfamily. As protease inhibitors, serpins have an array of functions including regulating blood coagulation, fibrinolysis, the complement pathway, angiogenesis, inflammation, tumor suppression, extracellular matrix remodeling, and cell motility. SERPINB1 regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Reactive bond 1 of SerpinB1 is specific for reaction with chymotrypsin-like protease such as cathepsin G, chymotrypsin or chymase. Reactive bond 2 of SerpinB1 is specific for reaction with elastase-like protease such as neutrophyl elastase, proteinase-3, pancreatic elastase or PSA. In addition, SERPINB1 also functions as a potent intracellular inhibitor of granzyme H.