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CI67

Recombinant Human T-cell-specific surface glycoprotein CD28/CD28

10ug

320

288

现货

国产

CI67

Recombinant Human T-cell-specific surface glycoprotein CD28/CD28

50ug

960

864

现货

国产

CI67

Recombinant Human T-cell-specific surface glycoprotein CD28/CD28

500ug

6160

5544

现货

国产

CI67

Recombinant Human T-cell-specific surface glycoprotein CD28/CD28

1mg

8800

7920

现货

国产

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  • Catalog# CI67
    Source Human cells
    Description Recombinant Mouse CD28 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asn20-Lys149) of Mouse CD28 fused with a polyhistidine and FC tag at the C-terminus.
    Names T-cell-specific surface glycoprotein CD28,CD28
    Accession # P31041
    Formulation Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    NKILVKQSPLLVVDSNEVSLSCRYSYNLLAKEFRASLYKGVNSDVEVCVGNGNFTYQPQFRSNAE FNCDGDFDNETVTFRLWNLHVNHTDIYFCKIEFMYPPPYLDNERSNGTIIHIKEKHLCHTQSSPK VDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDP EVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTI SKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSD GSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
    Background T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.