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CI65
Recombinant Human Thymidylate kinase/DTYMK
10ug
1200
1080
现货
国产
-
CI65
Recombinant Human Thymidylate kinase/DTYMK
50ug
3520
3168
现货
国产
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CI65
Recombinant Human Thymidylate kinase/DTYMK
500ug
12320
11088
现货
国产
-
CI65
Recombinant Human Thymidylate kinase/DTYMK
1mg
17600
15840
现货
国产
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Catalog# CI65 Source Human cells Description Recombinant Human DTYMK is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Lys212) of Human DTYMK fused with a polyhistidine tag at the C-terminus. Names Thymidylate kinase，dTMP kinase，DTYMK，CDC8, TMPK, TYMK Accession # P23919 Formulation Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKKSDVED HSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQPDVGLPKPDLV LFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDASKSIEAVHEDIRVLS EDAIRTATEKPLGELWKVDHHHHHHBackground Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyzes the conversion of dTMP to dTDP and catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest that the cDNA codes for authentic human dTMP kinase. The mRNA levels and enzyme activities corresponded to cell cycle progression and cell growth stages.