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CI97
Recombinant Human TNFRSF10B/MK/CD262/Dr5/Killer
10ug
400
360
现货
国产
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CI97
Recombinant Human TNFRSF10B/MK/CD262/Dr5/Killer
50ug
1200
1080
现货
国产
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CI97
Recombinant Human TNFRSF10B/MK/CD262/Dr5/Killer
500ug
9840
8856
现货
国产
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CI97
Recombinant Human TNFRSF10B/MK/CD262/Dr5/Killer
1mg
14080
12672
现货
国产
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Catalog# CI97 Source Human cells Description Recombinant mouse TNFRSF10B is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Asn53-Ser177) of mouse TNFRSF10Bfused with a Fc tag at the C-terminus.. Names Tumor necrosis factor receptor superfamily member 10B/Death receptor 5/MK/CD262/Tnfrsf10b/Dr5/Killer Accession # Q9QZM4 Formulation Lyophilized from a 0.2 μM filtered solution of 20mM PB,150mM NaCl,pH7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 2X PBS.
Please aliquot the reconstituted solution_x0000__x0016__x0000_u_x0000_u_x0000__x0014__x0000__x0016__x0000_v_x0000_v_x0000__x0000__x0000_ _x0000_v_x0000_v_x0000__x0014__x0000__x0016__x0000_䠀ŒѦStorage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 4 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence NPAHNRPAGLQRPEESPSRGPCLAGQYLSEGNCKPCREGIDYTSHSNHSLDSCILCTVCKEDKVV ETRCNITTNTVCRCKPGTFEDKDSPEICQSCSNCTDGEEELTSCTPRENRKCVSKTAWASVDDIE GRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFN WYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKG QPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFL YSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK*Background Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4). TNFRSF10B is highly expressed in heart, lung, lymphocytes, spleen and kidney. In addition, it is regulated by the tumor suppressor p53. TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL. It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.