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CH59
Recombinant Human YY1/Transcriptional repressor protein YY1
10ug
1200
1080
现货
国产
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CH59
Recombinant Human YY1/Transcriptional repressor protein YY1
50ug
3520
3168
现货
国产
-
CH59
Recombinant Human YY1/Transcriptional repressor protein YY1
500ug
12320
11088
现货
国产
-
CH59
Recombinant Human YY1/Transcriptional repressor protein YY1
1mg
17600
15840
现货
国产
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Catalog# CH59 Source E.coli Description Recombinant Human Transcriptional repressor protein YY1 is produced with our E. coli expression system. The target protein is expressed with sequence (Val221-Gly321) of Human YY1 fused with a 6His tag at the C-terminus.. Names Transcriptional repressor protein YY1,Delta transcription factor,INO80 complex subunit S,NF-E1,Yin and yang 1,INO80S Accession # P25490 Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MVTMWSSDEKKDIDHETVVEEQIIGENSPPDYSEYMTGKKLPPGGIPGIDLSDPKQLAEFARMKP RKIKEDDAPRTIACPHKGCTKMFRDNSAMRKHLHTHGLEHHHHHHBackground Transcriptional repressor protein YY1（YY1）contains 4 C2H2-type zinc fingers and belongs to the YY transcription factor family. Multifunctional transcription factor exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. The effect on transcription regulation of the protein is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect activation or repression via cofactor recruitment, or activation or repression by disruption of binding sites or conformational DNA changes. Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression.