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CG04

Recombinant Human Amphiregulin/AREG/AREGB/CRDGF/SDGF

10ug

480

432

现货

国产

CG04

Recombinant Human Amphiregulin/AREG/AREGB/CRDGF/SDGF

50ug

1440

1296

现货

国产

CG04

Recombinant Human Amphiregulin/AREG/AREGB/CRDGF/SDGF

500ug

12320

11088

现货

国产

CG04

Recombinant Human Amphiregulin/AREG/AREGB/CRDGF/SDGF

1mg

17600

15840

现货

国产

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  • Catalog# CG04
    Source E.coli
    Description Recombinant Human Amphiregulin/AREG is produced with our E. coli expression system. The target protein is expressed with sequence (Ser101-Lys198) of Human AREG.
    Names Amphiregulin, AR, Colorectum Cell-Derived Growth Factor, CRDGF, AREG, SDGF, AREGB
    Accession # P15514
    Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MSVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEH LEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSK
    Background Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy.