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CG53

Recombinant Human Ankyrin repeat and SOCS box protein 13/ASB13

10ug

1200

1080

现货

国产

CG53

Recombinant Human Ankyrin repeat and SOCS box protein 13/ASB13

50ug

3520

3168

现货

国产

CG53

Recombinant Human Ankyrin repeat and SOCS box protein 13/ASB13

500ug

13440

12096

现货

国产

CG53

Recombinant Human Ankyrin repeat and SOCS box protein 13/ASB13

1mg

19200

17280

现货

国产

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  • Catalog# CG53
    Source E.coli
    Description Recombinant Human Ankyrin repeat and SOCS box protein 13/ASB13 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asn278) of Human ASB13 fused with a 6His tag at the N-terminus.
    Names Ankyrin repeat and SOCS box protein 13, ASB13,
    Accession # Q8WXK3
    Formulation Supplied as a 0.2 μm filtered solution of PBS, pH 7.4, 4M Urea
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MNHKVHHHHHHMEPRAADGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSIT PLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTAS PLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHET ALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTPLTLSQLCRVN LRKATGVRGLEKIAKLNIPPRLIDYLSYN
    Background Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.