| Catalog# |
C832 |
| Source |
HEK293 |
| Description |
Recombinant Human Annexin A11 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Asp505) of Human Annexin-A11 fused with a 6His tag at the C-terminus. |
| Names |
Annexin A11, 56 kDa Autoantigen, Annexin XI, Annexin-11, Calcyclin-Associated Annexin 50, CAP-50, ANXA11, ANX11 |
| Accession # |
P50995 |
| Shipping |
The product is shipped at ambient temperature. |
| Storage |
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. |
| Purity |
Greater than 95% as determined by reducing SDS-PAGE. |
| Endotoxin |
Less than 0.1 ng/μg (1 IEU/μg). |
| Amino Acid Sequence |
MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTF GGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPG QPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVTPAVPPTQFGSRGTIT DAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSG NFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEA IRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAH LVAVFNEYQRMTGRDIEKSICREMSGDLEE GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTL IRIMVSRSETDLLDIRSEYKRMYGKS LYHDISGDTSGDYRKILLKICGGNDVDHHHHHH
|
| Background |
Annexin A11 is a cytoplasmic protein that belongs to the Annexin family. Annexin proteins have unique N-terminal domains and conserved C-terminal domains, which contains four annexin repeats. A pair of annexin repeats may form one binding site for calcium and phospholipid. Annexin A11 interacts with PDCD6 in a calcium-dependent manner and it interacts with KIF23 during cytokinesis. In addition, Annexin A11 is required for midbody formation and completion of the terminal phase of cytokinesis. |
