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CA34
Recombinant Human Anthrax toxin receptor 1/ANTXR1/ATR
10ug
840
756
现货
国产
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CA34
Recombinant Human Anthrax toxin receptor 1/ANTXR1/ATR
50ug
2520
2268
现货
国产
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CA34
Recombinant Human Anthrax toxin receptor 1/ANTXR1/ATR
500ug
12320
11088
现货
国产
-
CA34
Recombinant Human Anthrax toxin receptor 1/ANTXR1/ATR
1mg
17600
15840
现货
国产
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Catalog# CA34 Source Human Cells Description Recombinant Human Anthrax Toxin Receptor 1/ANTXR1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu33-Lys321) of Human ANTXR1 fused with a 6His tag at the C-terminus. Names Anthrax Toxin Receptor 1, Tumor Endothelial Marker 8, ANTXR1, ATR, TEM8 Accession # Q9H6X2 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence EDGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTE DREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSE REANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAE PSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMK AALQVSMNDGLSFISSSVIITTTHCSLHKVDHHHHHHBackground Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI).