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CE20
Recombinant Human ASS1/Argininosuccinate synthase
10ug
1200
1080
现货
国产
-
CE20
Recombinant Human ASS1/Argininosuccinate synthase
50ug
3520
3168
现货
国产
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CE20
Recombinant Human ASS1/Argininosuccinate synthase
500ug
12320
11088
现货
国产
-
CE20
Recombinant Human ASS1/Argininosuccinate synthase
1mg
17600
15840
现货
国产
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Catalog# CE20 Source E.coli Description Recombinant Human Argininosuccinate Synthase/ASS1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Lys412) of Human ASS1 fused with a 6His tag at the C-terminus. Names Argininosuccinate Synthase, Citrulline--Aspartate Ligase, ASS1, ASS Accession # P00966 Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 50mM Imidazole, 1mM DTT, 40% Glycerol, pH 7.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFE EARKKALKLGAKKVFIEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREG AKYVSHGATGKGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTP KNPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDRE VRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPLSLY NEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAKBackground Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.