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CE33
Recombinant Human ATG10/Ubiquitin-like-conjugating enzyme ATG10
10ug
1200
1080
现货
国产
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CE33
Recombinant Human ATG10/Ubiquitin-like-conjugating enzyme ATG10
50ug
3520
3168
现货
国产
-
CE33
Recombinant Human ATG10/Ubiquitin-like-conjugating enzyme ATG10
500ug
12320
11088
现货
国产
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CE33
Recombinant Human ATG10/Ubiquitin-like-conjugating enzyme ATG10
1mg
17600
15840
现货
国产
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Catalog# CE33 Source E.coli Description Recombinant Human Ubiquitin-Like-Conjugating Enzyme ATG10/ATG10 produced by E. coli expression system. The target protein is expressed with sequence (Met1-Thr190) of Human ATG10 fused with a 6His tag at the C-terminus. Names Ubiquitin-Like-Conjugating Enzyme ATG10, Autophagy-Related Protein 10, APG10-Like, ATG10 Accession # Q9H0Y0 Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MASMTGGQQMGRGSMEEDEFIGEKTFQRYCAEFIKHSQQIGDSWEWRPSKDCSDGYMCKIHFQIK NGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRAS FLDGRPLTLKDIWEGVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQK INKNVNYITLEHHHHHHBackground Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or ATG7.