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CG58
Recombinant Human ATG5/Autophagy protein 5/APG5L/ASP
10ug
840
756
现货
国产
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CG58
Recombinant Human ATG5/Autophagy protein 5/APG5L/ASP
50ug
2520
2268
现货
国产
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CG58
Recombinant Human ATG5/Autophagy protein 5/APG5L/ASP
500ug
12320
11088
现货
国产
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CG58
Recombinant Human ATG5/Autophagy protein 5/APG5L/ASP
1mg
17600
15840
现货
国产
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Catalog# CG58 Source E.coli Description Recombinant Human Autophagy protein 5/ATG5 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp275) of Human ATG5. Names Autophagy protein 5, APG5-like, Apoptosis-specific protein, APG5L, ASP, ATG5, Accession # Q9H1Y0 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris,0.2M NaCl,1mM DTT,40%glycerol, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDI SEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPSKDAIEAHFMSCMK EADALKHKSQVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPAEENGFRYIPFRIYQTTTE RPFIQKLFRPVAADGQLHTLGDLLKEVCPSAIDPEDGEKKNQVMIHGIEPMLETPLQWLSEHLSY PDNFLHISIIPQPTDBackground ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.