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C104
Recombinant Human BCL2L1/Bcl-2-like protein 1
10ug
840
756
现货
国产
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C104
Recombinant Human BCL2L1/Bcl-2-like protein 1
50ug
2520
2268
现货
国产
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C104
Recombinant Human BCL2L1/Bcl-2-like protein 1
500ug
12320
11088
现货
国产
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C104
Recombinant Human BCL2L1/Bcl-2-like protein 1
1mg
17600
15840
现货
国产
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Catalog# C104 Source E.coli Description Recombinant Human Bcl-2-Like Protein 1/BCL2L1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Arg212) of Human BCL2L1. Names Bcl-2-Like Protein 1, Bcl2-L-1, Apoptosis Regulator Bcl-X, BCL2L1, BCL2L, BCLX Accession # Q07817 Formulation Supplied as a 0.2 μm filtered solution of 20mM HEPES, 50mM KCl, 20% Glycerol, pH 7.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAV NGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNEL FRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELY GNNAAAESRKGQERFNRLEHHHHHHBackground Bcl-2-Like Protein 1 (BCL2L1) is a member of the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a mitochondrial membrane protein. BCL2L1 contains four motifs, BH1, BH2 and BH4. The BH4 motif is required for anti-apoptotic activity. The BH1 and BH2 motifs are required for both heterodimerization with other Bcl-2 family members and for repression of cell death. BCL2L1 regulates cell death by blocking the voltage-dependent anion channnel (VDAC) and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. In addition, BCL2L1 promotes apoptosis.