产品中心
-
产品货号
产品名称
规格
销售价
会员价
货期
产地
订购
-
CD45
Recombinant Human BDNF/NT-3 growth factors receptor/NTRK2/TRKB（K308A）
10ug
400
360
现货
国产
-
CD45
Recombinant Human BDNF/NT-3 growth factors receptor/NTRK2/TRKB（K308A）
50ug
1200
1080
现货
国产
-
CD45
Recombinant Human BDNF/NT-3 growth factors receptor/NTRK2/TRKB（K308A）
500ug
5200
4680
现货
国产
-
CD45
Recombinant Human BDNF/NT-3 growth factors receptor/NTRK2/TRKB（K308A）
1mg
6800
6120
现货
国产
- 产品简介
- 使用说明
- 相关产品
- 参考文献
- 购买咨询
Catalog# CD45 Source Human Cells Description Recombinant Human Neurotrophic Tyrosine Kinase Receptor Type 2/NTRK2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Cys32-Glu430) of Human TRKB(308K-A) fused with a polyhistidine tag at the C-terminus. Names BDNF/NT-3 Growth Factors Receptor, GP145-TrkB, Trk-B, Neurotrophic Tyrosine Kinase Receptor Type 2, TrkB Tyrosine Kinase, Tropomyosin-Related Kinase B, NTRK2, TRKB Accession # Q16620 Formulation Lyophilized from a 0.2 μm filtered solution of PBS，pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence CPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNL TIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKT LQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVP NMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITF LESPTSDHHWCIPFTVAGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNN GDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPSTD VTDKTGREHHHHHHBackground The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.