产品中心
-
产品货号
产品名称
规格
销售价
会员价
货期
产地
订购
-
CH21
Recombinant Human Betatrophin/C19orf80/TD26
10ug
1200
1080
现货
国产
-
CH21
Recombinant Human Betatrophin/C19orf80/TD26
50ug
3520
3168
现货
国产
-
CH21
Recombinant Human Betatrophin/C19orf80/TD26
500ug
13440
12096
现货
国产
-
CH21
Recombinant Human Betatrophin/C19orf80/TD26
1mg
19200
17280
现货
国产
- 产品简介
- 使用说明
- 相关产品
- 参考文献
- 购买咨询
Catalog# CH21 Source E. coli Description Recombinant Human Protein Betatrophin/C19orf80 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala22-Ala198) of Human Betatrophin Names Betatrophin,Angiopoietin-like protein 8,Lipasin,Angptl8 Accession # Q6UXH0 Formulation Supplied as a 0.2 μM filtered solution of 20mM Tris,150mM NaCl,pH8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MAPMGGPELAQHEELTLLFHGTLQLGQALNGVYRTTEGRLTKARNSLGLYGRTIELLGQEVSRGR DAAQELRASLLETQMEEDILQLQAEATAEVLGEVAQAQKVLRDSVQRLEVQLRSAWLGPAYREFE VLKAHADKQSHILWALTGHVQRQRREMVAQQHRLRQIQERLHTAALPALEHHHHHHBackground The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it acts as a blood lipid regulator by regulating serum triglyceride levels and possibly by promoting ANGPTL3 cleavage. It interacts with ANGPTL3. It predominantly expressed in liver and also expressed in adipose tissues. The ability of the protein to induce pancreatic beta cell proliferation is promising in diabetes therapy. Betatrophin treatment could supply or replace insulin injections by increasing the number of insulin-producing cells in diabetes.