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CF39
Recombinant Human Bisphosphoglycerate mutase/BPGM
10ug
760
684
现货
国产
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CF39
Recombinant Human Bisphosphoglycerate mutase/BPGM
50ug
2280
2052
现货
国产
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CF39
Recombinant Human Bisphosphoglycerate mutase/BPGM
500ug
12320
11088
现货
国产
-
CF39
Recombinant Human Bisphosphoglycerate mutase/BPGM
1mg
17600
15840
现货
国产
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Catalog# CF39 Source E.coli Description Recombinant Human Bisphosphoglycerate Mutase/BPGM is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Lys259) of Human BPGM fused with a 6His tag at the C-terminus. Names Bisphosphoglycerate Mutase, BPGM, 2,3-Bisphosphoglycerate Mutase Erythrocyte, 2,3-Bisphosphoglycerate Synthase, 2,3-Diphosphoglycerate Mutase, DPGM, BPG-Dependent PGAM, BPGM Accession # P07738 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris, 1mM DTT, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIH TAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESH PYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRAL LKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKKL EHHHHHHBackground Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia.