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CA75

Recombinant Human Bone marrow stromal antigen 2/BST2

10ug

840

756

现货

国产

CA75

Recombinant Human Bone marrow stromal antigen 2/BST2

50ug

2520

2268

现货

国产

CA75

Recombinant Human Bone marrow stromal antigen 2/BST2

500ug

12320

11088

现货

国产

CA75

Recombinant Human Bone marrow stromal antigen 2/BST2

1mg

17600

15840

现货

国产

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  • Catalog# CA75
    Source HEK293
    Description Recombinant Human Bone Marrow Stromal Antigen 2/BST2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asn49-Ser161) of Human BST2 fused with a polyhistidine tag at the C-terminus.
    Names Bone Marrow Stromal Antigen 2, BST-2, HM1.24 Antigen, Tetherin, CD317, BST2
    Accession # Q10589
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    NSEACRDGLRAVMECRNVTHLLQQELTEAQKGFQDVEAQAATCNHTVMALMASLDAEKAQGQKKV EELEGEITTLNHKLQDASAEVERLRRENQVLSVRIADKKYYPSSQDSSVDHHHHHH
    Background Bone Marrow Stromal Antigen 2 (BST2) is a single-pass type II membrane protein that belongs to the tetherin family. BST2 is predominantly expressed in the liver, lung, heart and placenta. BST2 is involved in the sorting of secreted proteins. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. BST2 is initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, it has also been shown to inhibit the release of other viruses such as retroviruses, filoviruses, arenaviruses, and herpes viruses. BST2 may play a role in B-cell activation in rheumatoid arthritis.