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CE47

Recombinant Human Bridging integrator 2/BIN2/BRAP1

10ug

1200

1080

现货

国产

CE47

Recombinant Human Bridging integrator 2/BIN2/BRAP1

50ug

3520

3168

现货

国产

CE47

Recombinant Human Bridging integrator 2/BIN2/BRAP1

500ug

12320

11088

现货

国产

CE47

Recombinant Human Bridging integrator 2/BIN2/BRAP1

1mg

17600

15840

现货

国产

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  • Catalog# CE47
    Source E.coli
    Description Recombinant Human Bridging Integrator 2/BIN2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Asn244) of Human BIN2 fused with a 6His tag at the N-terminus.
    Names Bridging Integrator 2, Breast Cancer-Associated Protein 1, BIN2, BRAP1
    Accession # Q9UBW5
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMAEGKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQ SASNFYQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLW EDYEEKLADQAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEE EFNKAQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEK QHSN
    Background Bridging Integrator 2 (BIN2) is a cytoplasmic protein. BIN2 contains one BAR domain and Interacts with BIN1. BIN2 is highly expressed in some hematopoietic tissues, including peripheral blood, thymus, colon and placenta. BIN2 is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling. Genetic studies show that BIN2 is inhibited in response to BR perception at the cell surface to relieve its inhibitory effects on downstream targets.