| Catalog# |
C911 |
| Source |
HEK293 |
| Description |
Recombinant Human Calmodulin/CALM1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala2-Lys149) of Human Calmodulin fused with a polyhistidine tag at the C-terminus. |
| Names |
Calmodulin, CaM, CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII |
| Accession # |
P62158 |
| Shipping |
The product is shipped at ambient temperature. |
| Storage |
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. |
| Purity |
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
| Endotoxin |
Less than 0.1 ng/μg (1 IEU/μg). |
| Amino Acid Sequence |
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG61NGT IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE121EVDEM IREADIDGDGQVNYEEFVQMMTAKVDHHHHHH
|
| Background |
Calmodulin belongs to the calmodulin family. Calmodulin contains four EF-hand domains, each of which binds a calcium ion. Calmodulin is a multifunctional intermediate messager protein that transduces calcium signals by binding calcium ions and then modifies its interactions with various target proteins. Calmodulin is involved in many crucial processes such as inflammation, metabolism, apoptosis, short-term and long-term memory, immune response and so on. Calmodulin undergoes two post-translation modification, ubiquitination and phosphorylation, resulting in a decreased activity. |
