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CG02
Recombinant Human Calpain-2 catalytic subunit/CAPN2/CANPL2
10ug
1200
1080
现货
国产
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CG02
Recombinant Human Calpain-2 catalytic subunit/CAPN2/CANPL2
50ug
3520
3168
现货
国产
-
CG02
Recombinant Human Calpain-2 catalytic subunit/CAPN2/CANPL2
500ug
13440
12096
现货
国产
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CG02
Recombinant Human Calpain-2 catalytic subunit/CAPN2/CANPL2
1mg
19200
17280
现货
国产
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Catalog# CG02 Source E.coli Description Recombinant Human Calpain-2 Catalytic Subunit/CAPN2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Leu700) of Human CAPN2 fused with a 6His tag at the C-terminus. Names Calpain-2 Catalytic Subunit, Calcium-Activated Neutral Proteinase 2, CANP 2, Calpain M-Type, Calpain Large Polypeptide L2, Calpain-2 Large Subunit, Millimolar-Calpain, M-Calpain, CAPN2, CANPL2 Accession # P17655 Formulation Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, 2mM DTT, pH 7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MAGIAAKLAKDREAAEGLGSHERAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGP YSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQS FQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEAL SGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVK GHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDGEFW MSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIK LEEEDEDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLT NRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANL EEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD SDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARF ADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVLVEHHHHHHBackground Calpain-2 Catalytic Subunit (CANP2) is an intracellular cysteine protease. It contains 1 calpain catalytic domain and 3 EF-hand domains. CANP2 is a member of the peptidase C2 family of intracellular Ca2+-regulated cysteine proteases. These ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits (CANP2) associated with a common small, regulatory subunit (CAPNS1). CANP2 is activated by 200-1000 micromolar concentrations of calcium and inhibited by calpastatin. CANP2 is calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.