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C934
Recombinant Human CANT1/Calcium Activated Nucleotidase 1
10ug
1200
1080
现货
国产
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C934
Recombinant Human CANT1/Calcium Activated Nucleotidase 1
50ug
3520
3168
现货
国产
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C934
Recombinant Human CANT1/Calcium Activated Nucleotidase 1
500ug
12320
11088
现货
国产
-
C934
Recombinant Human CANT1/Calcium Activated Nucleotidase 1
1mg
17600
15840
现货
国产
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Catalog# C934 Source HEK293 Description Recombinant Human Calcium Activated Nucleotidase 1/CANT1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Arg63-Ile401) of Human CANT1 fused with a polyhistidine tag at the C-terminus. Names Soluble Calcium-Activated Nucleotidase 1, SCAN-1, Apyrase Homolog, Putative MAPK-Activating Protein PM09, Putative NF-Kappa-B-Activating Protein 107, CANT1, SHAPY Accession # Q8WVQ1 Shipping The product is shipped at ambient temperature. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence RPAPGRPPTHNAHNWRLGQAPANWYNDTYPLSPPQRTPAGIRYRIAVIADLDTESRAQEENTWFS YLKKGYLTLSDSGDKVAVEWDKDHGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVVYQIEG SKAVPWVILSDGDGTVEKGFKAEWLAVKDERLYVGGLGKEWTTTTGDVVNENPEWVKVVGYKGSV DHENWVSNYNALRAAAGIQPPGYLIHESACWSDTLQRWFFLPRRASQERYSEKDDERKGANLLLS ASPDFGDIAVSHVGAVVPTHGFSSFKFIPNTDDQIIVALKSEEDSGRVASYIMAFTLDGRFLLPE TKIGSVKYEGIEFIVDHHHHHHBackground Soluble Calcium-Activated Nucleotidase 1 (CANT1) belongs to the apyrase family. CANT1 is a single-pass type II membrane protein and functions as a calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. It also has low activity towards ADP and even lower activity towards ATP. Defects in CANT1 are the cause of Desbuquois dysplasia, a chondrodysplasia characterized by severe prenatal and postnatal growth retardation, joint laxity, short extremities, progressive scoliosis, round face, midface hypoplasia, prominent bulging eyes.