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C110

Recombinant Human Carbonic Anhydrase VB/CA5B

10ug

1200

1080

现货

国产

C110

Recombinant Human Carbonic Anhydrase VB/CA5B

50ug

3520

3168

现货

国产

C110

Recombinant Human Carbonic Anhydrase VB/CA5B

500ug

12320

11088

现货

国产

C110

Recombinant Human Carbonic Anhydrase VB/CA5B

1mg

17600

15840

现货

国产

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  • Catalog# C110
    Source E.coli
    Description Recombinant Human Carbonic Anhydrase 5B/CA5B is produced with our E. coli expression system. The target protein is expressed with sequence (Cys34-Pro317) of Human CA5B.
    Names Carbonic Anhydrase 5B Mitochondrial, Carbonate Dehydratase VB, Carbonic Anhydrase VB, CA-VB, CA5B
    Accession # Q9Y2D0
    Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MCSLYTCTYKTRNRALHPLWESVDLVPGGDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWN NGYSFLVEFEDSTDKSVIKGGPLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAV RFENFEDAALEENGLAVIGVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDY WTYSGSLTTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTV RSSFRHDYVLNVQAKPKPATSQATPLEHHHHHH
    Background Carbonic Anhydrase 5B (CA5B) is a member of alpha-carbonic anhydrase family (CAs) that catalyze the reversible hydration of carbon dioxide. CAs is associated with many biological processes, including calcification, respiration, bone resorption, acid-base balance and the formation of aqueous humor. CA5B is highly expressed in heart, pancreas, kidney, placenta, lung, and skeletal muscle, but it is restricted to the liver. CA5B is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA-VA. CA5B is inhibited by coumarins, sulfonamide derivatives such as acetazolamide (AZA), saccharin, and Foscarnet.