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C112
Recombinant Human Carbonic Anhydrase VIII/CA8
10ug
480
432
现货
国产
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C112
Recombinant Human Carbonic Anhydrase VIII/CA8
50ug
1440
1296
现货
国产
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C112
Recombinant Human Carbonic Anhydrase VIII/CA8
500ug
12320
11088
现货
国产
-
C112
Recombinant Human Carbonic Anhydrase VIII/CA8
1mg
17600
15840
现货
国产
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Catalog# C112 Source E.coli Description Recombinant Human Carbonic Anhydrase 8/CA8 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala2-Gln290) of Human CA8. Names Carbonic Anhydrase-Related Protein, CARP, Carbonic Anhydrase VIII, CA-VIII, CA8, CALS Accession # P35219 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 1mM DTT, pH 8.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MADLSFIEDTVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSL LDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHT VNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKS KTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGA ELVEGCDGILGDNFRPTQPLSDRVIRAAFQLEHHHHHHBackground Carbonic Anhydrase 8 (CA8) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Because CA8 has some sequence similarity with other known carbonic anhydrase genes, it was firstly called as CA-related protein. Nevertheless, CA8 does not have a carbonic anhydrase catalytic activity. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3), which is a congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mild mental retardation.