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C567
Recombinant Human Carbonic Anhydrase XIV/CA14(C-polyHis)
10ug
1200
1080
现货
国产
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C567
Recombinant Human Carbonic Anhydrase XIV/CA14(C-polyHis)
50ug
3520
3168
现货
国产
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C567
Recombinant Human Carbonic Anhydrase XIV/CA14(C-polyHis)
500ug
12320
11088
现货
国产
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C567
Recombinant Human Carbonic Anhydrase XIV/CA14(C-polyHis)
1mg
17600
15840
现货
国产
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Catalog# C567 Source HEK293 Description Recombinant Human Carbonic Anhydrase 14/CA14 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ala16-Met290) of Human CA14 fused with a polyhistidine tag at the C-terminus. Names Carbonic Anhydrase 14, Carbonate Dehydratase XIV, Carbonic Anhydrase XIV, CA-XIV, CA14 Accession # Q9ULX7 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence ADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLH NNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYD SLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYF RYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVF ASFIQAGSSYTTGEMVDHHHHHHBackground Carbonic Anhydrase 14 (CA14) is a single-pass type I membrane protein which belongs to the alpha-carbonic anhydrase family. CA14 catalyzes the reversible hydration of carbon dioxide reaction of CO2 + H2O = HCO3- + H+, which is fundamental to many processes such as respiration. CA14 is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine and Inhibited by coumarins, saccharin, sulfonamide derivatives such as acetazolamide (AZA) and Foscarnet. CA14 is highly expressed in all parts of the central nervous system. The active site of most carbonic anhydrases 14 contains a zinc ion, and one of the functions of the CA14 is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues.