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C594

Recombinant Human Carboxypeptidase A4/CPA4

10ug

1200

1080

现货

国产

C594

Recombinant Human Carboxypeptidase A4/CPA4

50ug

3520

3168

现货

国产

C594

Recombinant Human Carboxypeptidase A4/CPA4

500ug

12320

11088

现货

国产

C594

Recombinant Human Carboxypeptidase A4/CPA4

1mg

17600

15840

现货

国产

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  • Catalog# C594
    Source HEK293
    Description Recombinant Human Carboxypeptidase A4/CPA4 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gly17-Tyr421) of Human CPA4 fused with a polyhistidine tag at the C-terminus.
    Names Carboxypeptidase A4, Carboxypeptidase A3, CPA4, CPA3
    Accession # Q9UI42
    Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mm NaCl, pH 7.5
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    GQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFNRPVDVLVPSVSLQAFKSFLR SQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARR VKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSI LEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEV YHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKA LASVSGTEYQVGPTCTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETW LGLKTIMEHVRDNLYVDHHHHHH
    Background Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. Carboxypeptidases cleave amino acids from the C-terminus of proteins and peptides and many are metalloproteases. They have distinct expression patterns and different specificities for example, preferentially cleaving aromatic (carboxypeptidase As) or basic (carboxypeptidase Bs) residues. Several, such as carboxypeptidase Xs, have lost their catalytic activity. Carboxypeptidases play important roles in digestion of food, processing of bioactive peptides and blood coagulation. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition.