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CG70
Recombinant Human Casein kinase I isoform gamma-2/CSNK1G2
10ug
760
684
现货
国产
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CG70
Recombinant Human Casein kinase I isoform gamma-2/CSNK1G2
50ug
2280
2052
现货
国产
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CG70
Recombinant Human Casein kinase I isoform gamma-2/CSNK1G2
500ug
12320
11088
现货
国产
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CG70
Recombinant Human Casein kinase I isoform gamma-2/CSNK1G2
1mg
17600
15840
现货
国产
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Catalog# CG70 Source E.coli Description Recombinant Human Casein kinase I isoform gamma-2/CSNK1G2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met18-Lys415) of Human CSNK1G2 fused with a 6His tag at the N-terminus. Names Casein kinase I isoform gamma-2, CK1G2, CSNK1G2 Accession # P78368 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris,500mM NaCl,10% Glycerol,1mM DTT, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGELRL GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLE DLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLA KEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKA DTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFV FDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSKNQALNSTNGELNADDPTAGHSNAPITA PAEVEVADETKCCCFFKRRKRKSLQRHK*Background 'CSNK1G2 is a cytoplasmic protein which contains one protein kinase domain. It is amember of the CK1 Ser/Thr protein kinase family of the large casein kinase I (CKI) subfamily. CSNK1G2 participates in Wnt signaling, involves in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. It regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses.'