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CI41

Recombinant Human CASK/Peripheral plasma membrane protein CASK

10ug

1200

1080

现货

国产

CI41

Recombinant Human CASK/Peripheral plasma membrane protein CASK

50ug

3520

3168

现货

国产

CI41

Recombinant Human CASK/Peripheral plasma membrane protein CASK

500ug

12320

11088

现货

国产

CI41

Recombinant Human CASK/Peripheral plasma membrane protein CASK

1mg

17600

15840

现货

国产

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  • Catalog# CI41
    Source Human Cells
    Description Recombinant Human Peripheral plasma membrane protein CASK/Calcium/calmodulin-dependent serine protein kinase/Protein lin-2 homolog is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Tyr898) of Human CASK fused with a polyhistidine tag at the C-terminus.
    Names Peripheral plasma membrane protein CASK, Calcium/calmodulin-dependent serine protein kinase, Protein lin-2 homolog, CASK, LIN2
    Accession # O14936-4
    Formulation Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASI CHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALR YCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREP YGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLD PAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPP EELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKI NTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDE ALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMH GGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCEDLPSTT QPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIP SPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLV LLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEY GSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQ RLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVYVDHHHHHH*
    Background Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene.It belongs to the MAGUK family. CASK / LIN2 contains one guanylate kinase-like domain, two L27 domains, one PDZ (DHR) domain, one protein kinase domain and one SH3 domain. This protein is a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. It interacts with the transcription factor TBR1 and binds to several cell-surface proteins including amyloid precursor protein, neurexins and syndecans.Unlike many protein kinases, it does not require a divalent cation such as magnesium for catalytic activity.