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CA23

Recombinant Human CD116/GM-CSF-R-alpha/CSF2RA

10ug

1200

1080

现货

国产

CA23

Recombinant Human CD116/GM-CSF-R-alpha/CSF2RA

50ug

3520

3168

现货

国产

CA23

Recombinant Human CD116/GM-CSF-R-alpha/CSF2RA

500ug

12320

11088

现货

国产

CA23

Recombinant Human CD116/GM-CSF-R-alpha/CSF2RA

1mg

17600

15840

现货

国产

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  • Catalog# CA23
    Source Human Cells
    Description Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit α/CSF2RA is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu23-Gly320) of Human CSF2RA fused with a 6His tag at the C-terminus.
    Names Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alpha, GM-CSF-R-Alpha, GMCSFR-Alpha, GMR-Alpha, CDw116, CD116, CSF2RA, CSF2R, CSF2RY
    Accession # P15509
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    EKSDLRTVAPASSLNVRFDSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREIC LHEGVTFEVHVNTSQRGFQQKLLYPNSGREGTAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFL YIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSLLDTKKIER FNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYN FPSSEPRAKHSVKIRAADVRILNWSSWSEAIEFGSDDGVDHHHHHH
    Background Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit α (CSF2RA) is a single-pass type I membrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms being membrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophage colony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4).