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CD06
Recombinant Human BTLA/B-andT-lymphocyte attenuator/CD272
10ug
1200
1080
现货
国产
-
CD06
Recombinant Human BTLA/B-andT-lymphocyte attenuator/CD272
50ug
3520
3168
现货
国产
-
CD06
Recombinant Human BTLA/B-andT-lymphocyte attenuator/CD272
500ug
13440
12096
现货
国产
-
CD06
Recombinant Human BTLA/B-andT-lymphocyte attenuator/CD272
1mg
19200
17280
现货
国产
-
CD06
Recombinant Human CD272/B-andT-lymphocyte attenuator/BTLA
10ug
1200
1080
现货
国产
-
CD06
Recombinant Human CD272/B-andT-lymphocyte attenuator/BTLA
50ug
3520
3168
现货
国产
-
CD06
Recombinant Human CD272/B-andT-lymphocyte attenuator/BTLA
500ug
13440
12096
现货
国产
-
CD06
Recombinant Human CD272/B-andT-lymphocyte attenuator/BTLA
1mg
19200
17280
现货
国产
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Catalog# CD06 Source Human Cells Description Recombinant Human B-andT-lymphocyte attenuator/BTLA/CD272 is produced by our mammalian expression system. The target protein is expressed with sequence (Lys31-Leu150) of Human BTLA fused with FC tag at the C-terminus. Names B- and T-Lymphocyte Attenuator, B- and T-Lymphocyte-Associated Protein, CD272, BTLA Accession # Q7Z6A9 Formulation Lyophilized from a 0.2 μm filtered solution of PBS，pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence KESCDVQLYIKRQSEHSILAGDPFELECPVKYCANRPHVTWCKLNGTTCVKLEDRQTSWKEEKNI SFFILHFEPVLPNDNGSYRCSANFQSNLIESHSTTLYVTGKQNELSDTAGREINLVDDIEGRMDE PKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDG VEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREP QVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLT VDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKBackground B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response. BTLA also is a ligand for tumor necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses.