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C577
Recombinant Human CD3D/T-cell surface glycoprotein CD3 delta chain
10ug
1024
921.6
现货
国产
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C577
Recombinant Human CD3D/T-cell surface glycoprotein CD3 delta chain
50ug
3080
2772
现货
国产
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C577
Recombinant Human CD3D/T-cell surface glycoprotein CD3 delta chain
500ug
12320
11088
现货
国产
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C577
Recombinant Human CD3D/T-cell surface glycoprotein CD3 delta chain
1mg
17600
15840
现货
国产
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Catalog# C577 Source HEK293 Description Recombinant Human T-Cell Surface Glycoprotein CD3 Delta/CD3D is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Phe22-Ala105) of Human CD3D fused with a polyhistidine tag at the C-terminus. Names T-Cell Surface Glycoprotein CD3 Delta Chain, T-Cell Receptor T3 Delta Chain, CD3d, CD3D, T3D Accession # P04234 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence FKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGTDIYKDKESTV QVHYRMCQSCVELDPATVAVDHHHHHHBackground CD3D is a single-pass type I membrane protein which Contains 1 ITAM domain. T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T-B+NK+ SCID), which is a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.