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CA29

Recombinant Human CD79B/B29

10ug

1200

1080

现货

国产

CA29

Recombinant Human CD79B/B29

50ug

3520

3168

现货

国产

CA29

Recombinant Human CD79B/B29

500ug

12320

11088

现货

国产

CA29

Recombinant Human CD79B/B29

1mg

17600

15840

现货

国产

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  • Catalog# CA29
    Source HEK293
    Description Recombinant Human CD79B is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ala29-Asp159) of Human CD79B fused with a 6His tag at the C terminus.
    Names B-Cell Antigen Receptor Complex-Associated Protein Beta Chain, B-Cell-Specific Glycoprotein B29, Ig-Beta, Immunoglobulin-Associated B29 Protein, CD79b, CD79B, B29, IGB
    Accession # P40259
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    ARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEK GRMEESQNESLATLTIQGIRFEDNGIYFCQQKCNNTSEVYQGCGTELRVMGFSTLAQLKQRNTLK DVDHHHHHH
    Background CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.