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CE18
Recombinant Human CDO1/Cysteine dioxygenase type 1
10ug
400
360
现货
国产
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CE18
Recombinant Human CDO1/Cysteine dioxygenase type 1
50ug
1120
1008
现货
国产
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CE18
Recombinant Human CDO1/Cysteine dioxygenase type 1
500ug
4920
4428
现货
国产
-
CE18
Recombinant Human CDO1/Cysteine dioxygenase type 1
1mg
7040
6336
现货
国产
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Catalog# CE18 Source E.coli Description Recombinant Human Cysteine Dioxygenase Type 1/CDO1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Asn200) of Human CDO1 fused with a 6His tag at the N-terminus. Names Cysteine Dioxygenase Type 1, Cysteine Dioxygenase Type I, CDO, CDO-I, CDO1 Accession # Q16878 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 10% Glycerol, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMEQTEVLKPRTLADLIRILHQLFAGDEVNVEEVQAIMEAYESDPT EWAMYAKFDQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTNSHCFLKMLQGNLKETLFAWP DKKSNEMVKKSERVLRENQCAYINDSVGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKN KVTMTFHSKFGIRTPNATSGSLENNBackground Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic concentration of intracellular free cysteine within a proper narrow range. CDO1 is able to alter intracellular cysteine levels and glutathione levels.