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CE14
Recombinant Human CLIC4/Chloride intracellular channel protein 4
10ug
1200
1080
现货
国产
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CE14
Recombinant Human CLIC4/Chloride intracellular channel protein 4
50ug
3520
3168
现货
国产
-
CE14
Recombinant Human CLIC4/Chloride intracellular channel protein 4
500ug
12320
11088
现货
国产
-
CE14
Recombinant Human CLIC4/Chloride intracellular channel protein 4
1mg
17600
15840
现货
国产
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Catalog# CE14 Source E.coli Description Recombinant Human Chloride Intracellular Channel Protein 4/CLIC4 produced by E. coli expression system. The target protein is expressed with sequence (Met1-Lys253) of Human CLIC4 fused with a 6His tag at the N-terminus. Names Chloride Intracellular Channel Protein 4, Intracellular Chloride Ion Channel Protein p64H1, CLIC4 Accession # Q9Y696 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMIL WLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPK HPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFST RKFLDGNEMTLADCNLLPKLHIVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEV EIAYSDVAKRLTKBackground Chloride Intracellular Channel Protein 4 (CLIC4) is a 253 amino acid single-pass membrane protein that localizes to both the nucleus and the cytoplasm and contains one GST C-terminal domain. CLIC4 is expressed in various tissues and exhibits an intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). CLIC4 acts as a monomer which is able to form selective ion channels in target proteins, thus facilitating the transport of chloride and other ions. CLIC4 is believed to have a role in apoptosis and is able to translocate to the nucleus under stress conditions. CLIC4 has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis.