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C212
Recombinant Human CLIC5/Chloride intracellular channel protein 5
10ug
1200
1080
现货
国产
-
C212
Recombinant Human CLIC5/Chloride intracellular channel protein 5
50ug
3520
3168
现货
国产
-
C212
Recombinant Human CLIC5/Chloride intracellular channel protein 5
500ug
12320
11088
现货
国产
-
C212
Recombinant Human CLIC5/Chloride intracellular channel protein 5
1mg
17600
15840
现货
国产
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Catalog# C212 Source E.coli Description Recombinant Human Chloride Intracellular Channel Protein 5/CLIC5 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ser251) of Human CLIC5 fused with a His tag at the N-terminus. Names Chloride Intracellular Channel Protein 5, CLIC5 Accession # Q9NZA1 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLK GVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRE SNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKF LDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELA YADVAKRLSRSBackground Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 can insert into membranes and form selective ion channels regulated by actin that may transport chloride ions. It may play a role in the regulation of transepithelial ion absorption and secretion. CLIC5 specifically associates with the cytoskeleton of placenta microvilli. CLIC5 is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture.