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CB08

Recombinant Human Creatine kinase U-type/CKMT1A

10ug

760

684

现货

国产

CB08

Recombinant Human Creatine kinase U-type/CKMT1A

50ug

2000

1800

现货

国产

CB08

Recombinant Human Creatine kinase U-type/CKMT1A

500ug

12320

11088

现货

国产

CB08

Recombinant Human Creatine kinase U-type/CKMT1A

1mg

17600

15840

现货

国产

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  • Catalog# CB08
    Source HEK293
    Description Recombinant Human Creatine kinase U-type/CKMT1A is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala40-His417) of Human CKMT1A fused with a polyhistidine tag at the C-terminus.
    Names CKMT1, U-MtCK, acidic-type mitochondrial creatine kinase, creatine kinase U-type, mitochondrial, creatine kinase, mitochondrial 1 (ubiquitous), mia-CK, ubiquitous mitochondrial creatine kinase
    Accession # P12532
    Formulation Supplied as a 0.2 μM filtered solution of PBS, pH 7.4
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    ASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKT VGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLSSRVRTGRS IRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPL LTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQE RGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATG GVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQDIRIPTPVIHTKHVDHHHHHH
    Background Creatine kinase U-type, mitochondrial(CKMT1A) is a peripheral membrane protein,It contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain.It belongs to the ATP:guanido phosphotransferase family. CKMT1 is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It exists as two isoenzymes, sarcomeric MtCK (CKMT2) and ubiquitous MtCK, encoded by separate genes. CKMT1 occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric CKMT1.