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CC98
Recombinant Human CTHRC1/Collagen triple helix repeat-containing protein 1
10ug
1200
1080
现货
国产
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CC98
Recombinant Human CTHRC1/Collagen triple helix repeat-containing protein 1
50ug
3520
3168
现货
国产
-
CC98
Recombinant Human CTHRC1/Collagen triple helix repeat-containing protein 1
500ug
13440
12096
现货
国产
-
CC98
Recombinant Human CTHRC1/Collagen triple helix repeat-containing protein 1
1mg
19200
17280
现货
国产
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Catalog# CC98 Source HEK293 Description Recombinant Human Collagen triple helix repeat-containing protein 1/CTHRC1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ser31-Lys243) of Human CTHRC1 fused with a polyhistidine tag at the C-terminus. Names Accession # Q96CG8 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence SEIPKGKQKAQLRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLR ESFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFT FNGAECSGPLPIEAIIYLDQGSPEMNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGD ASTGWNSVSRIIIEELPKVDHHHHHHBackground Collagen triple helix repeat-containing protein 1 is a protein that in humans is encoded by the CTHRC1 gene. It acts as a negative regulator of collagen matrix deposition. It may cause the disease of Barrett esophagus . Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes.