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C587
Recombinant Human CD301/CLEC10A
10ug
640
576
现货
国产
-
C587
Recombinant Human CD301/CLEC10A
50ug
1760
1584
现货
国产
-
C587
Recombinant Human CD301/CLEC10A
500ug
12320
11088
现货
国产
-
C587
Recombinant Human CD301/CLEC10A
1mg
17600
15840
现货
国产
-
C587
Recombinant Human C-Type Lectin Domain Family 10 Member A/CLEC10A
10ug
640
576
现货
国产
-
C587
Recombinant Human C-Type Lectin Domain Family 10 Member A/CLEC10A
50ug
1760
1584
现货
国产
-
C587
Recombinant Human C-Type Lectin Domain Family 10 Member A/CLEC10A
500ug
12320
11088
现货
国产
-
C587
Recombinant Human C-Type Lectin Domain Family 10 Member A/CLEC10A
1mg
17600
15840
现货
国产
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Catalog# C587 Source HEK293 Description Recombinant Human C-Type Lectin Domain Family 10 Member A/CLEC10A is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln61-His316) of Human CLEC10A fused with a polyhistidine tag at the C-terminus. Names C-Type Lectin Domain Family 10 Member A, C-Type Lectin Superfamily Member 14, Macrophage Lectin 2, CD301, CLEC10A, CLECSF13, CLECSF14, HML Accession # Q8IUN9 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence QNSKFQRDLVTLRTDFSNFTSNTVAEIQALTSQGSSLEETIASLKAEVEGFKQERQAGVSELQEH TTQKAHLGHCPHCPSVCVPVHSEMLLRVQQLVQDLKKLTCQVATLNNNASTEGTCCPVNWVEHQD SCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMGLSDPEGAWKWVDGTD YATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVCQRPYHWVCEAGLGQTSQESHVDHH HHHHBackground C-Type Lectin Domain Family 10 Member A (CLEC10A) is a type II transmembrane C-type lectin that is expressed on immature myleloid dendritic cells and alternatively activated (tolerogenic) macrophages. CLEC10A/MGL binds and internalizes molecules with terminal nonsialylated GalNAc carbohydrates such as the Tn carcinoma antigen. CLEC10A/MGL also binds the GP envelope glycoprotein on Marburg and Ebola viruses and enhances viral entry and infectivity. It constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. CLEC10A is thought to participate in the recognition of molecules from both altered self and pathogens due to its monosaccharide specificity for Gal and N-acetylgalactosamine (GalNAc). Human and rat carry a single gene for CLEC10A/MGL, while mouse has two closely related MGL1 and MGL2 genes.