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C588
Recombinant Human C-Type Lectin Domain Family 4 Member E/CLEC4E
10ug
840
756
现货
国产
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C588
Recombinant Human C-Type Lectin Domain Family 4 Member E/CLEC4E
50ug
2520
2268
现货
国产
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C588
Recombinant Human C-Type Lectin Domain Family 4 Member E/CLEC4E
500ug
12320
11088
现货
国产
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C588
Recombinant Human C-Type Lectin Domain Family 4 Member E/CLEC4E
1mg
17600
15840
现货
国产
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Catalog# C588 Source HEK293 Description Recombinant Human C-Type Lectin Domain Family 4 Member E/CLEC4E is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Arg41-Leu219) of Human CLEC4E fused with a polyhistidine tag at the C-terminus. Names C-Type Lectin Domain Family 4 Member E, C-Type Lectin Superfamily Member 9, Macrophage-Inducible C-Type Lectin, CLEC4E, CLECSF9, MINCLE Accession # Q9ULY5 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence RCVVTFRIFQTCDEKKFQLPENFTELSCYNYGSGSVKNCCPLNWEYFQSSCYFFSTDTISWALSL KNCSAMGAHLVVINSQEEQEFLSYKKPKMREFFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEP NNIATLEDCATMRDSSNPRQNWNDVTCFLNYFRICEMVGINPLNKGKSLVDHHHHHHBackground C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E functions as a downstream target of C/EBP β and is thought to play a role in the inflammatory response, possibly via transcriptional control of C/EBP β. CLEC4E may play a role in the response to inflammatory stimuli in peritoneal macrophages and may be involved in immune surveillance processes under transcriptional control of CEBPB. Human CLEC4E shares 67% sequence identity with its mouse counterpart, suggesting a similar function between species. CLEC-4E exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to a natural killer gene complex region on human chromosome 12.