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C597

Recombinant Human CXCL1/GRO

10ug

640

576

现货

国产

C597

Recombinant Human CXCL1/GRO

50ug

1760

1584

现货

国产

C597

Recombinant Human CXCL1/GRO

500ug

12320

11088

现货

国产

C597

Recombinant Human CXCL1/GRO

1mg

17600

15840

现货

国产

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  • Catalog# C597
    Source HEK293
    Description Recombinant Human C-X-C Motif Chemokine 1/CXCL1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ala35-Asn107) of Human CXCL1 fused with a polyhistidine tag at the C-terminus.
    Names Growth-Regulated Alpha Protein, C-X-C Motif Chemokine 1, GRO-Alpha(1-73), Melanoma Growth Stimulatory Activity, MGSA, Neutrophil-Activating Protein 3, NAP-3, CXCL1, GRO, GRO1, GROA, MGSA, SCYB1
    Accession # P09341
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, pH 7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    ASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEK MLNSDKSNVDHHHHHH
    Background Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.