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C243
Recombinant Human Cyclin-dependent kinase 4 inhibitor C/p18-INK4c/CDKN2C
10ug
1200
1080
现货
国产
-
C243
Recombinant Human Cyclin-dependent kinase 4 inhibitor C/p18-INK4c/CDKN2C
50ug
3520
3168
现货
国产
-
C243
Recombinant Human Cyclin-dependent kinase 4 inhibitor C/p18-INK4c/CDKN2C
500ug
12320
11088
现货
国产
-
C243
Recombinant Human Cyclin-dependent kinase 4 inhibitor C/p18-INK4c/CDKN2C
1mg
17600
15840
现货
国产
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Catalog# C243 Source E.coli Description Recombinant Human Cyclin-Dependent Kinase 4 Inhibitor C/CDKN2C is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Gln168) of Human CDKN2C fused with a His tag at the N-terminus. Names Cyclin-Dependent Kinase 4 Inhibitor C, Cyclin-Dependent Kinase 6 Inhibitor, p18-INK4c, p18-INK6, CDKN2C, CDKN6 Accession # P42773 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 8.0 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVM KLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA AKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQBackground Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in skeletal muscle, pancreas, and heart. CDKN2C inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB and prevent the activation of the CDK kinases. Studies have been shown the roles of CDKN2C gene in regulating spermatogenesis, as well as in suppressing tumorigenesis.